Calcific uremic arteriolopathy in hemodialyzed patients.
نویسندگان
چکیده
In the present article, we discuss the case of 67-year-old female patient diagnosed with inferior limbs calciphylaxis and hemodialyzed since 2006. The clinical manifestations and pathological lab findings are typical for this rare and extremely severe complication in chronic hemodialyzed individuals. The favorable treatment response to sodium thiosulfate, not often used as elected therapy in international studies, represents the particularity of the case.
منابع مشابه
Calcific Uremic Arteriolopathy in Peritoneal Dialysis Populations
Calciphylaxis or calcific uremic arteriolopathy is an infrequent complication of end stage kidney disease. It is characterized by arteriolar medial calcification, thrombotic cutaneous ischemia, tissue necrosis often leading to ulceration, secondary infection and increased mortality rates. Current, multimodality treatment involves local wound care, well-controlled calcium, phosphate and parathyr...
متن کاملPatterns of vascular calcification in patients with end‐stage renal disease and calcific uremic arteriolopathy
Calcific uremic arteriolopathy or calciphylaxis is a rare and potentially fatal condition, which manifests as skin ischemia and necrosis, usually seen in patients with end-stage renal disease. It is frequently associated with vascular calcification visible on plain radiographs, which can occur in various patterns.
متن کاملCalcific uremic arteriolopathy
Calcific uremic arteriolopathy (CUA)/calciphylaxis is an important cause of morbidity and mortality in patients with chronic kidney disease requiring renal replacement. Once thought to be rare, it is being increasingly recognized and reported on a global scale. The uremic milieu predisposes to multiple metabolic toxicities including increased levels of reactive oxygen species and inflammation. ...
متن کاملCalciphylaxis- a Brief Review
Calciphylaxis, or calcific uremic arteriolopathy, is a rare vascular disease that is seen in end stage renal disease and renal transplant patients; however, there are cases reported in literature with normal renal function but little systematic information is available on calciphylaxisfrom nonuremic causes. This article reviews the etio-pathogenesis, clinical features, laboratory abnormalities,...
متن کاملSuccessfully Treated Calcific Uremic Arteriolopathy: Two Cases of a High Anion Gap Metabolic Acidosis with Intravenous Sodium Thiosulfate
Calcific uremic arteriolopathy (CUA) is a rare and potentially fatal disorder of calcification involving subcutaneous small vessels and fat in patients with renal insufficiency. We describe the successful use of intravenous sodium thiosulfate (STS) for the treatment of CUA in two patients. The first case was complicated by the development of a severe anion gap metabolic acidosis, which was acco...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Chirurgia
دوره 108 5 شماره
صفحات -
تاریخ انتشار 2013